Lamin A/C antibody (AA 319-566)

Catalog No. ABIN327798

This anti-Lamin A/C antibody is a Mouse Monoclonal antibody detecting Lamin A/C in WB, IHC, FACS and IHC (fro). Suitable for Human, Mouse, Rat and Sheep.

Quick Overview for Lamin A/C antibody (AA 319-566) (ABIN327798)

Target: Lamin A/C (LMNA)

Reactivity: Human, Mouse, Rat, Sheep

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lamin A/C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Lamin A/C Antibody

Binding Specificity: AA 319-566

Specificity: Reacts against lamins A and C. Epitope located between residues 319-566. Species cross-reactivity: Human, mouse, rat, bovine, hamster, canine, and sheep.

Purification: Protein G purified

Immunogen: Lamin A, C.

Type of Immunogen: Protein

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: Flo (1:50 - 1:100), IHC, IHC-Fr, WB (1:50 - 1:500)

Usage: Suitable for use in Immunohistochemistry (frozen sections), Flow Cytometry, and Western Blot. Western Blot: 1:50-1:500. Immunohistochemistry: 1:50-1:100. Flow Cytometry: 1:50-1:100. Optimum dilutions to be determined by researcher. Hybridoma: P3X63-Ag8.653myeloma cells w/spleen cells from Balb/c mice.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide, 40 % glycerol. No stabilizing proteins added.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Lamin A/C

Target: Lamin A/C (LMNA)

Alternative Name: LMNA / Lamin A/C

Background: Name/Gene ID: LMNA

Synonyms: LMNA, 70 kDa lamin, CDCD1, CMD1A, EMD2, FPLD, IDC, FPL, FPLD2, Lamin A/C, Lamin, LFP, LMNC, LMN1, LMNL1, HGPS, Prelamin-A/C, PRO1, Lamin A, Lamin A/C-like 1, LGMD1B, CDDC, CMT2B1, LDP1

This antibody detects: LMNA / Lamin A+C

Gene ID: 4000

UniProt: P02545

Pathways: Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus