Laminin antibody

Catalog No. ABIN335387

Product Details anti-Laminin Antibody

Target: Laminin (LN)

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Laminin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Specificity: Human and mouse.

Purification: Purified

Immunogen: A5 is a rat monoclonal IgG2a antibody derived by fusion of mouse myeloma cells with spleen cells from a Fisher rat immunized with a laminin preparation from the EHS mouse tumor.

Clone: A5

Isotype: IgG2a

Application Details

Application Notes: A5 reacts with laminin. APPLICATIONS A5 is suitable for immunocytochemistry and immunohistochemistry on frozen tissues. Optimal antibody dilution should be determined by titration, recommended range is 1:25 - 1:200 for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent.

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-Laminin antibody (ABIN335387)

Ljubimova, Lakhter, Loksh, Yong, Riedinger, Miner, Sorokin, Ljubimov, Black: "Overexpression of alpha4 chain-containing laminins in human glial tumors identified by gene microarray analysis." in: Cancer research, Vol. 61, Issue 14, pp. 5601-10, (2001) (PubMed).

Ljubimov, Bartek, Couchman, Kapuller, Veselov, Kovarik, Perevoshchikov, Krutovskikh: "Distribution of individual components of basement membrane in human colon polyps and adenocarcinomas as revealed by monoclonal antibodies." in: International journal of cancer. Journal international du cancer, Vol. 50, Issue 4, pp. 562-6, (1992) (PubMed).

Target Details for Laminin

Target: Laminin (LN)

Alternative Name: Laminin (LN Products)

Synonyms: LAMC1 antibody, laminin antibody, laminin, beta 2 (laminin S) antibody, LAMB2 antibody

Background: Basement membrane components play an important role in cell adhesion, locomotion, differentiation and embryonic compartmentalization. Laminin anchors cells to the basement membrane through interactions with integrins at the cell surface and collagens in the basement membrane.