Nibrin antibody (C-Term)

Catalog No. ABIN342381

The Mouse Monoclonal anti-Nibrin antibody (Clone 1D7) (ABIN342381) specifically detects Nibrin in WB and IP. The antibody is reactive with Human samples.

Quick Overview for Nibrin antibody (C-Term) (ABIN342381)

Target: Nibrin (NBN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Nibrin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 1D7

Product Details anti-Nibrin Antibody

Binding Specificity: C-Term

Specificity: Recognizes the 95 kD nibrin protein which contains a forkhead-associated domain that is adjacent to BRCT, a breast cancer C- terminal domain involved in protein- protein interactions. p95/nibrin is a member of the Mre11/Rad50 double- strand break repair complex.

Purification: Protein G purified

Immunogen: Fusion protein containing the complete coding region of human p95/nibrin expressed in E. coli.

Type of Immunogen: Fusion protein

Isotype: IgG1

Application Details

Application Notes: Approved: IP (1 - 2 μg/mL), WB

Usage: Western Blot: A band of 95 kD is detected.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4

Handling Advice: Avoid freeze/thaw cycles.

Storage: -80 °C

Storage Comment: Store at -70°C, avoid freeze/thaw cycles.

Target Details for Nibrin

Target: Nibrin (NBN)

Alternative Name: NBN / NBS1 / Nibrin

Background: Name/Gene ID: NBN

Synonyms: NBN, ATV, AT-V2, Nibrin, NBS1, AT-V1, NBS, p95

Gene ID: 4683

UniProt: O60934

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response