TRIB3 antibody

Catalog No. ABIN347475

The Rabbit Polyclonal anti-TRIB3 antibody (ABIN347475) specifically detects TRIB3 in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for TRIB3 antibody (ABIN347475)

Target: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TRIB3 Antibody

Specificity: Reacts with human 39 kDa TRIB-3 protein

Cross-Reactivity (Details): May cross react with monkeys due to sequence homology.

Purification: Antiserum

Immunogen: Synthetic peptide derived from human TRIB-3

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC1:50 - 1:500 WB1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for TRIB3

Target: TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))

Alternative Name: Tribbles Homolog 3

Background: TRIB-3 is expressed in various tissues with high levels in liver, pancreas, peripheral blood leukocytes and bone marrow but also in primary lung, colon and breast cancer. It is a negative regulator of NF-kappaB and can sensitize cells to apoptosis induced by TNF or TRAIL.

Gene ID: 57761

UniProt: Q96RU7

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha