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CHMP6 antibody (C-Term)

CHMP6 Reactivity: Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN350231
  • Target See all CHMP6 Antibodies
    CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))
    Binding Specificity
    • 14
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 28
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 29
    • 2
    Rabbit
    Clonality
    • 31
    Polyclonal
    Conjugate
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    This CHMP6 antibody is un-conjugated
    Application
    • 27
    • 19
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    Specific for CHMP6.
    Cross-Reactivity
    Mouse, Rat
    Cross-Reactivity (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogen
    A synthetic peptide from the c-terminal region of mouse CHMP6 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 95% identity with rat's.
    Isotype
    IgG
    Top Product
    Discover our top product CHMP6 Primary Antibody
  • Application Notes
    IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))
    Alternative Name
    CHMP6 (CHMP6 Products)
    Synonyms
    chmp6 antibody, vps20 antibody, 2400004G01Rik antibody, VPS20 antibody, RGD1565325 antibody, chmp6l antibody, flj11749l antibody, wu:fb79d02 antibody, zgc:110067 antibody, charged multivesicular body protein 6 antibody, charged multivesicular body protein 6 L homeolog antibody, charged multivesicular body protein 6 S homeolog antibody, charged multivesicular body protein 6b antibody, LOC100280982 antibody, chmp6.L antibody, chmp6.S antibody, CHMP6 antibody, chmp6 antibody, Tsp_08316 antibody, Chmp6 antibody, chmp6b antibody
    Background
    FUNCTION: Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In the ESCRT-III complex, it probably serves as an acceptor for ESCRT-II complex on endosomal membranes. SUBUNIT: Component of the endosomal sorting required for transport complex III (ESCRT-III), at least composed of CHMP1A, CHMP1B, CHMP2A, CHMP2B, CHMP3/VPS24, CHMP4A/SHAX2, CHMP4B/SHAX1, CHMP4C/SHAX3, CHMP5/SNF7DC2 and CHMP6/VPS20. In the complex, it interacts directly with CHMP4A, CHMP4B and CHMP4C. Interacts directly with SNF8, VPS25 and VPS36 components of the ESCRT-II complex. SUBCELLULAR LOCATION: Intracytoplasmic membrane. Endosome membrane, Lipid-anchor . Note: Localizes to endosomal membranes.,Vesicle Protein Sorting,Charged multivesicular body protein 6, Chromatin-modifying protein 6
    UniProt
    P0C0A3
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