TPCN2 antibody (Cytoplasmic Domain)

Catalog No. ABIN351016

Product Details anti-TPCN2 Antibody

Target: TPCN2 (Two Pore Segment Channel 2 (TPCN2))

Binding Specificity: Cytoplasmic Domain

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPCN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for TPC2.

Immunogen: A synthetic peptide from a cytoplasmic domain of mouse TPC2 (Two pore calcium channel protein 2) conjugated to an immunogenic carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

References for anti-TPCN2 antibody (ABIN351016)

Arndt, Castonguay, Arlt, Meyer, Hassan, Borth, Zierler, Wennemuth, Breit, Biel, Wahl-Schott, Gudermann, Klugbauer, Boekhoff: "NAADP and the two-pore channel protein 1 participate in the acrosome reaction in mammalian spermatozoa." in: Molecular biology of the cell, Vol. 25, Issue 6, pp. 948-64, (2014) (PubMed).

Target Details for TPCN2

Target: TPCN2 (Two Pore Segment Channel 2 (TPCN2))

Alternative Name: TPC2 (TPCN2 Products)

Synonyms: fi42c05 antibody, im:7140344 antibody, wu:fi42c05 antibody, zgc:152898 antibody, MGC115225 antibody, SHEP10 antibody, TPC2 antibody, BC025890 antibody, D830047E22Rik antibody, two pore segment channel 2 antibody, two pore segment channel 2 L homeolog antibody, two pore calcium channel protein 2 antibody, tpcn2 antibody, Tpcn2 antibody, TPCN2 antibody, tpcn2.L antibody, LOC100444397 antibody

Background: Function: May function as one of the major voltage-gated Ca2+ channel (VDCC) across the plasma membrane.
Subcellular location: Membrane, Multi-pass membrane protein. Also known as: Two pore calcium channel protein 2, Voltage-dependent calcium channel protein TPC2, TPCN2.