TP53BP1 antibody

Catalog No. ABIN353939

The Rabbit Polyclonal anti-TP53BP1 antibody is suitable to detect TP53BP1 in samples from Human and Mouse. It has been validated for IHC, WB, IF, ICC and IHC (p).

Quick Overview for TP53BP1 antibody (ABIN353939)

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53BP1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TP53BP1 Antibody

Specificity: Specific for human 53BP1 protein. Species cross-reactivity: Reacts with human in Western Blot and immunocytochemistry/immunofluorescence and it reacts with mouse in immunocytochemistry/immunofluorescence (Western Blot has not been done using this antibody

Purification: Immunoaffinity purified

Immunogen: A synthetic peptide, which represented a portion of human tumor protein p53 binding protein 1 encoded exon 19 (LocusLink ID 7158).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: ICC (1:200 - 1:1000), IF (1:200 - 1:1000), IHC, IHC-P (1:200 - 1:1000), WB (1:2000 - 1:10000)

Usage: Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry (paraffin-embedded sections) and Immunocytochemistry. Immunofluorescence: 1:200-1:1000. Western Blot: 1:2000-1:10000. A band at ~220kD is seen on SDS-PAGE. Immunocytochemistry: 1:200-1:1000. Positive control: U205, 293T, and MO59K cell lysates (human) and MEF lysates (mouse).

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-citrate/phosphate,  pH 7.5, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for TP53BP1

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Alternative Name: TP53BP1 / 53BP1

Background: Name/Gene ID: TP53BP1

Synonyms: TP53BP1, 53BP1, p202, p53-binding protein 1, p53-binding protein 53bp1, p53BP1

Gene ID: 7158

UniProt: Q12888

Pathways: DNA Damage Repair