MTMR4 antibody (C-Term)

Catalog No. ABIN359023

Product Details anti-MTMR4 Antibody

Target: MTMR4 (Myotubularin Related Protein 4 (MTMR4))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTMR4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to MTMR4.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MTMR4.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for MTMR4

Target: MTMR4 (Myotubularin Related Protein 4 (MTMR4))

Alternative Name: MTMR4 (MTMR4 Products)

Synonyms: zfyve11 antibody, fyve-dsp2 antibody, FYVE-DSP2 antibody, ZFYVE11 antibody, AA596759 antibody, ESTM44 antibody, mKIAA0647 antibody, myotubularin related protein 4 antibody, myotubularin related protein 4 L homeolog antibody, Mtmr4 antibody, MTMR4 antibody, mtmr4 antibody, mtmr4.L antibody

Background: MTMR, a member of the myotubularin family, encodes an intracellular protein of 1,195 amino acids, and shares approximately 47 % sequence identity with MTMR3, spiking to over 70 % identity in the catalytic domain and the double zinc finger (FYVE) motif. PCR analysis detects expression of MTMR4 in all human tissues examined except lung, small intestine, stomach, salivary gland, adrenal gland, and uterus. Subcellular localization of MTMR4 in transfected HeLa cells showed a perinuclear distribution, similar to that seen with MTMR3. MTMR4 dephosphorylates para-nitrophenylphosphate and phosphatidylinositol 3-phosphate.Synonyms: FYVE domain-containing dual specificity protein phosphatase 2, KIAA0647, Myotubularin-related protein 4, ZFYVE11, Zinc finger FYVE domain-containing protein 11

Gene ID: 9110, 5874

UniProt: Q9NYA4

Pathways: Inositol Metabolic Process