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RIPK3 antibody (Middle Region)
RIPK3
Reactivity: Human, Mouse
WB, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RIPK3 Antibody
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Target
See all RIPK3 Antibodies
RIPK3
(Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
Binding Specificity
All epitopes for RIPK3 antibodies
Middle Region
Reactivity
All reactivities for RIPK3 antibodies
Human, Mouse
Host
All hosts for RIPK3 antibodies
Rabbit
Clonality
All clonalities for RIPK3 antibodies
Polyclonal
Conjugate
All conjugates for RIPK3 antibodies
This RIPK3 antibody is un-conjugated
Application
All applications for RIPK3 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody detects RIPK3 / RIP3.
Purification
Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human RIPK3.
Isotype
Ig Fraction
Top Product
Discover our top product RIPK3 Primary Antibody
Alternatives
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Application Details
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Application Notes
ELISA1: 1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Target Details for RIPK3
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Target
RIPK3
(Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
Alternative Name
RIPK3 / RIP3 (RIPK3 Products )
Synonyms
RIPK3 antibody, RIP3 antibody, 2610528K09Rik antibody, AW107945 antibody, Rip3 antibody, Hcyp2 antibody, receptor interacting serine/threonine kinase 3 antibody, receptor interacting serine/threonine kinase 3 S homeolog antibody, receptor-interacting serine-threonine kinase 3 antibody, RIPK3 antibody, ripk3.S antibody, Ripk3 antibody
Background
The product of the RIPK3 gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.Synonyms: RIP-3, RIP-like protein kinase 3, Receptor-interacting protein 3, Receptor-interacting serine/threonine-protein kinase 3
Molecular Weight
56901 Da.
Gene ID
11035, 9606
UniProt
Q9Y572
Pathways
Activation of Innate immune Response , Toll-Like Receptors Cascades
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