Isocitrate Dehydrogenase antibody (Middle Region)

Catalog No. ABIN359618

Product Details anti-Isocitrate Dehydrogenase Antibody

Target: Isocitrate Dehydrogenase (IDH)

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Isocitrate Dehydrogenase antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to IDH1.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human IDH1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Isocitrate Dehydrogenase

Target: Isocitrate Dehydrogenase (IDH)

Alternative Name: Isocitrate Dehydrogenase / IDH (IDH Products)

Synonyms: CG7176 antibody, CT22171 antibody, Dmel\\CG7176 antibody, IDH antibody, IDH-NADP antibody, Idh-NADP antibody, idh antibody, isocitrate dehydrogenase antibody, l(3)L3852 antibody, F20D21.16 antibody, F20D21_16 antibody, SMU.672 antibody, icd antibody, Isocitrate dehydrogenase antibody, isocitrate dehydrogenase antibody, isocitrate dehydrogenase, NADP-dependent antibody, Monomeric isocitrate dehydrogenase antibody, ankyrin repeat domain 26-like antibody, Idh antibody, ICDH antibody, idh antibody, icd antibody, SSO_RS10660 antibody, JK_RS08640 antibody, LOC618625 antibody

Background: IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.Synonyms: Cytosolic NADP-isocitrate dehydrogenase, ICDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, PICD, cytoplasmic Isocitrate dehydrogenase [NADP]

Gene ID: 3417, 9606

UniProt: O75874