AXL antibody (N-Term)

Catalog No. ABIN359784

The Rabbit Polyclonal anti-AXL antibody (ABIN359784) specifically detects AXL in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for AXL antibody (N-Term) (ABIN359784)

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AXL antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-AXL Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to AXL.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human AXL.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for AXL

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Alternative Name: AXL / UFO

Background: AXL, a member of the AXL/UFO subfamily of Tyr protein kinases, may function as a signal transducer between specific cell types of mesodermal origin. This Type I membrane protein has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia. The protein contains 2 putative fibronectin type III domains and 2 putative immunoglobulin-like C2-type domains.Synonyms: Tyrosine-protein kinase receptor UFO

Gene ID: 558, 9606

UniProt: P30530

Pathways: RTK Signaling, Cellular Response to Molecule of Bacterial Origin