RTN4R antibody (Extracellular Domain)

Catalog No. ABIN360933

The Rat Monoclonal anti-RTN4R antibody (Clone 3D66) (ABIN360933) specifically detects RTN4R in WB. The antibody is reactive with Mouse samples.

Quick Overview for RTN4R antibody (Extracellular Domain) (ABIN360933)

Target: RTN4R (Reticulon 4 Receptor (RTN4R))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This RTN4R antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 3D66

Product Details anti-RTN4R Antibody

Binding Specificity: Extracellular Domain

Specificity: This antibody detects Mouse Nogo receptor. Other species not tested.

Purification: Protein A/G Affinity Chromatography

Immunogen: Purified Mouse Recombinant Nogo receptor extracellular domain

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: PBS, None

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RTN4R

Target: RTN4R (Reticulon 4 Receptor (RTN4R))

Alternative Name: Nogo 66 Receptor

Background: Nogo Receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. It is also a receptor for Nogo A (RTN4), OMG and MAG. Nogo Receptor (Nogo R, NgR), also named reticulon 4 receptor, is a glycosylphosphatidylinositol (GPI)-anchored protein that belongs to the family of leucine-rich repeat (LRR) proteins. It is expressed predominantly in the central nervous systems on neurons and their axons.Synonyms: NOGOR, Nogo receptor, RTN4R, Reticulon-4 receptor

Gene ID: 65079

NCBI Accession: NP_075358

UniProt: Q99PI8

Pathways: Neurotrophin Signaling Pathway