Stargazin antibody (C-Term)

Catalog No. ABIN361402

Product Details anti-Stargazin Antibody

Target: Stargazin (CACNG2) (Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2))

Binding Specificity: C-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stargazin antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Specific for the ~36k stargazin protein. Immunolabeling of the stargazin band is blocked by preadsorption with the peptide used as antigen.

Cross-Reactivity: Rat (Rattus)

Predicted Reactivity: mouse

Purification: Antigen Affinity Purified from Pooled Serum

Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH

Application Details

Application Notes: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Target Details for Stargazin

Target: Stargazin (CACNG2) (Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2))

Alternative Name: CACNG2 (CACNG2 Products)

Synonyms: cacng2 antibody, zgc:64200 antibody, CACNG2 antibody, stargazin antibody, AW060990 antibody, B230105C07Rik antibody, B930041E13Rik antibody, stargazer antibody, stg antibody, wag antibody, waggler antibody, Ipr328 antibody, MRD10 antibody, calcium voltage-gated channel auxiliary subunit gamma 2 antibody, calcium channel, voltage-dependent, gamma subunit 2a antibody, calcium channel, voltage-dependent, gamma subunit 2 antibody, CACNG2 antibody, cacng2a antibody, cacng2 antibody, Cacng2 antibody

Background: Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated (Tomita et al., 2005, Priel et al., 2005) that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors (Choi et al., 2002). Anti-Stargazin Western blot of rat synaptic membrane (SPM) showing specific immunolabeling of the ~ 36k stargazin protein.

Molecular Weight: '36 kDa

Gene ID: 12300

UniProt: O88602

Pathways: Skeletal Muscle Fiber Development