SYN1 antibody

Catalog No. ABIN361409

Product Details anti-SYN1 Antibody

Target: SYN1 (Synapsin I (SYN1))

Reactivity: Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Specificity: Specific for the ~78k synapsin I doublet in Western blots of rat brain extracts. Immunolabeling blocked by preadsorption of antibody with the protein used to generate the antibody.

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: Antigen Affinity Purified from Pooled Serum

Immunogen: Native protein purified from bovine brain

Application Details

Application Notes: Recommended Dilution: WB: 1:1000 IHC, IF (frozen sections, unpublished observations): 1:2000 IP: 1 µg per 200 µg lysate Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized

Storage: -20 °C

Target Details for SYN1

Target: SYN1 (Synapsin I (SYN1))

Alternative Name: SYN1 (SYN1 Products)

Synonyms: SYN1a antibody, SYN1b antibody, SYNI antibody, Syn-1 antibody, SYN I antibody, si:dkey-90n12.3 antibody, synapsin I antibody, synapsin I L homeolog antibody, SYN1 antibody, Syn1 antibody, syn1.L antibody, syn1 antibody

Background: Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002, Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation (Moore and Bernstein, 1989, Stone et al., 1994). Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001, Kao et al., 2002). Anti-Synapsin I Western blot of 10 ug of rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~78k synapsin I doublet protein.

Molecular Weight: '78 kDa

Gene ID: 281510

UniProt: P17599