Tyrosine Hydroxylase antibody

Catalog No. ABIN361413

Cited in 5+ publications. The Rabbit Polyclonal anti-Tyrosine Hydroxylase antibody (ABIN361413) specifically detects Tyrosine Hydroxylase in WB, IHC, ICC and ELISA. The antibody is reactive with Rat samples.

Quick Overview for Tyrosine Hydroxylase antibody (ABIN361413)

Target: Tyrosine Hydroxylase (TH)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tyrosine Hydroxylase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), ELISA

Product Details anti-Tyrosine Hydroxylase Antibody

Specificity: Specific for endogenous levels of the ~60 kDa tyrosine hydroxylase protein.

Cross-Reactivity: Mammalian

Characteristics: Our Tyrosine Hydroxylase rabbit polyclonal primary antibody is produced in-house. It detects Tyrosine Hydroxylase and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, ICC.

Purification: Prepared from pooled rabbit serum by affinity purification using a column to which the fusion protein immunogen was coupled.

Immunogen: SDS-denatured, native rat tyrosine hydroxylase purified from pheochromocytoma.

Isotype: IgG

Application Details

Application Notes:

Dilution Range: ICC: 1:500-1:1000

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.15 mg/mL

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Expiry Date: 12 months

References for anti-Tyrosine Hydroxylase antibody (ABIN361413)

Sanyal, Dutta, Camara, Chandran, Koller, Watson, Sengupta, Ysselstein, Montenegro, Cannon, Rochet, Mattoo: "Alpha-Synuclein Is a Target of Fic-Mediated Adenylylation/AMPylation: Possible Implications for Parkinson's Disease." in: Journal of molecular biology, Vol. 431, Issue 12, pp. 2266-2282, (2020) (PubMed).

Brindley, Bauer, Walker, Quinlan, Carneiro, Sze, Blakely, Currie: "Adrenal serotonin derives from accumulation by the antidepressant-sensitive serotonin transporter." in: Pharmacological research, Vol. 140, pp. 56-66, (2019) (PubMed).

de Rus Jacquet, Timmers, Ma, Thieme, McCabe, Vest, Lila, Rochet: "Lumbee traditional medicine: Neuroprotective activities of medicinal plants used to treat Parkinson's disease-related symptoms." in: Journal of ethnopharmacology, Vol. 206, pp. 408-425, (2018) (PubMed).

de Rus Jacquet, Tambe, Ma, McCabe, Vest, Rochet: "Pikuni-Blackfeet traditional medicine: Neuroprotective activities of medicinal plants used to treat Parkinson's disease-related symptoms." in: Journal of ethnopharmacology, Vol. 206, pp. 393-407, (2018) (PubMed).

Salvatore, Waymire, Haycock: "Depolarization-stimulated catecholamine biosynthesis: involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ." in: Journal of neurochemistry, Vol. 79, Issue 2, pp. 349-60, (2001) (PubMed).

Target Details for Tyrosine Hydroxylase

Target: Tyrosine Hydroxylase (TH)

Alternative Name: Tyrosine Hydroxylase

Background:

Synonyms: Dystonia 14 antibody, DYT14 antibody, DYT5b antibody, EC 1.14.16.2 antibody, OTTHUMP00000011225 antibody, OTTHUMP00000011226 antibody, ple antibody, Protein Pale antibody, TH antibody, The antibody, TY3H_HUMAN antibody, TYH antibody, Tyrosine 3 hydroxylase antibody, Tyrosine 3 monooxygenase antibody, Tyrosine 3-hydroxylase antibody, Tyrosine 3-monooxygenase antibody, Tyrosine hydroxylase antibody

Description Logic: Our Tyrosine Hydroxylase rabbit polyclonal primary antibody is produced . It detects Tyrosine Hydroxylase and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, ICC.

Gene Name Alternatives: TH

Molecular Weight: 60 kDa

Gene ID: 25085

UniProt: P04177

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour