Potassium Channel (pSer503) antibody

Catalog No. ABIN361488

Cited in 1 publication. The Rabbit Polyclonal anti-Potassium Channel antibody (ABIN361488) specifically detects Potassium Channel in WB, IHC, ELISA and ICC. The antibody is reactive with Rat samples.

Quick Overview for Potassium Channel (pSer503) antibody (ABIN361488)

Target: Potassium Channel

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Product Details

Binding Specificity: pSer503

Specificity: Specific for endogenous levels of the ~100 kDa Kv3.1 voltage-gated potassium channel protein phosphorylated at Ser503.

Cross-Reactivity: Hamster, Mouse, Rat

Characteristics: Our Potassium Channel, Voltage-Gated, Kv3.1 Subunit (Ser503) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Potassium Channel, Voltage-Gated, Kv3.1 Subunit (Ser503) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, ICC.

Purification: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: The antigen is a phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser503 of the rat voltage-gated potassium channel Kv3.1, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes:

Dilution Range: ICC: 1:400

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Expiry Date: 12 months

References

Sagi, Medrihan, George, Barney, McCabe, Greengard: "Emergence of 5-HT5A signaling in parvalbumin neurons mediates delayed antidepressant action." in: Molecular psychiatry, Vol. 25, Issue 6, pp. 1191-1201, (2020) (PubMed).

Target Details

Target: Potassium Channel

Background:

Synonyms: C230009H10Rik antibody, FLJ41162 antibody, FLJ42249 antibody, FLJ43491 antibody, Kcnc1 antibody, KCNC1 antibody, KCNC1_HUMAN antibody, Kcr2 1 antibody, KShIIIB antibody, Kv3.1 antibody, Kv4 antibody, MGC129855 antibody, NGK2 antibody, Potassium voltage-gated channel subfamily C member 1 antibody, Shaw antibody, Voltage gated potassium channel antibody, Voltage gated potassium channel subunit Kv3.1 antibody, Voltage-gated potassium channel subunit Kv3.1 antibody, Voltage-gated potassium channel subunit Kv4 antibody

Description Logic: Our Potassium Channel, Voltage-Gated, Kv3.1 Subunit (Ser503) rabbit polyclonal phosphospecific primary antibody is produced . It detects Potassium Channel, Voltage-Gated, Kv3.1 Subunit (Ser503) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, ICC.

Gene Name Alternatives: KCNC1

Molecular Weight: 100 kDa

Gene ID: 25327

UniProt: P25122