p53 antibody (pSer392)

Catalog No. ABIN361513

This Rabbit Polyclonal antibody specifically detects p53 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for p53 antibody (pSer392) (ABIN361513)

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This p53 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-p53 Antibody

Binding Specificity: pSer392

Specificity: Specific for endogenous levels of the ~53 kDa p53 protein phosphorylated at Ser392 ~53 kDa p53 protein phosphorylated at Ser392. The immunolabeling is completely eliminated by treatment with λ-phosphatase.

Cross-Reactivity: Human, Rat

Predicted Reactivity: human

Characteristics: Our p53 (Ser392) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects p53 (Ser392) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Purification: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser392 of human p53, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes:

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Expiry Date: 12 months

Target Details for p53

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Alternative Name: TP53

Background:

Synonyms: Antigen NY-CO-13 antibody, BCC7 antibody, Cellular tumor antigen p53 antibody, FLJ92943 antibody, LFS1 antibody, Mutant tumor protein 53 antibody, p53 antibody, p53 tumor suppressor antibody, P53_HUMAN antibody, Phosphoprotein p53 antibody, Tp53 antibody, Transformation related protein 53 antibody, TRP53 antibody, Tumor protein 53 antibody, Tumor protein p53 antibody, Tumor suppressor p53 antibody

Description Logic: Our p53 (Ser392) rabbit polyclonal phosphospecific primary antibody is produced . It detects p53 (Ser392) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: TP53

Molecular Weight: 53 kDa

Gene ID: 7157

UniProt: P04637

Pathways: p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect