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KRT8 antibody (pSer74)

The Rabbit Polyclonal anti-KRT8 antibody is suitable to detect KRT8 in samples from Human. It has been validated for IF.

Catalog No. ABIN362394

$350.90

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Quick Overview for KRT8 antibody (pSer74) (ABIN362394)

Target

See all KRT8 Antibodies

KRT8 (Keratin 8 (KRT8))

Reactivity

Human

Host

Rabbit

Clonality

Polyclonal

Conjugate

This KRT8 antibody is un-conjugated

Application

Immunofluorescence (IF)

Discover our top product KRT8 Primary Antibody

Binding Specificity
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16

13

12

10

8

8

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2

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2

1

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1
pSer74

Specificity

The antibody detects endogenous level of Keratin 8 only when phosphorylated at serine 74.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen

Peptide sequence around phosphorylation site of pSer74 (L-L-S (p) -P-L) derived from Human Keratin 8 (CK8) . Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotype

IgG
anti-Keratin 8 (KRT8) antibody
KRT8 Reactivity: Human, Mouse WB, IHC, FACS, ICC, IHC (fro) Host: Mouse Monoclonal M20 unconjugated

anti-Keratin 8 (KRT8) (Ser726), (Ser731) antibody
KRT8 Reactivity: Human WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Keratin 8 (KRT8) (AA 92-393) antibody
KRT8 Reactivity: Human WB, IHC, IF, FACS, ICC Host: Rabbit Polyclonal unconjugated

anti-Keratin 8 (KRT8) (pSer432) antibody
KRT8 Reactivity: Human, Rat, Mouse WB, IHC, IF, ELISA, ICC Host: Rabbit Polyclonal unconjugated

anti-Keratin 8 (KRT8) (AA 91-381) antibody
KRT8 Reactivity: Human, Rat, Monkey, Dog WB, IHC, IF, IHC (p) Host: Mouse Monoclonal 1B12 unconjugated

anti-Keratin 8 (KRT8) antibody
KRT8 Reactivity: Human, Rat, Zebrafish (Danio rerio) WB, IHC, IF, FACS Host: Mouse Monoclonal H1 unconjugated

anti-Keratin 8 (KRT8) (AA 1-483) antibody
KRT8 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Keratin 8 (KRT8) antibody
KRT8 Reactivity: Human, Cow, Rabbit, Pig, Sheep WB, IHC, IF, FACS Host: Mouse Monoclonal B22-1 unconjugated

anti-Keratin 8 (KRT8) (AA 391-483) antibody
KRT8 Reactivity: Human WB, IHC, ELISA, ICC Host: Mouse Monoclonal 8A5D12 unconjugated

anti-Keratin 8 (KRT8) (N-Term) antibody
KRT8 Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae WB, IHC Host: Rabbit Polyclonal unconjugated

Application Notes

Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target

KRT8 (Keratin 8 (KRT8))

Alternative Name

Keratin 8

Background

Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

Molecular Weight

55 kDa

NCBI Accession

NP_002264

UniProt

P05787