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ERBB3 antibody (pTyr1328)
ERBB3
Reactivity: Human, Mouse, Rat
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ERBB3 Antibody
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Target
See all ERBB3 Antibodies
ERBB3
(Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
Binding Specificity
All epitopes for ERBB3 antibodies
pTyr1328
Reactivity
All reactivities for ERBB3 antibodies
Human, Mouse, Rat
Host
All hosts for ERBB3 antibodies
Rabbit
Clonality
All clonalities for ERBB3 antibodies
Polyclonal
Conjugate
All conjugates for ERBB3 antibodies
This ERBB3 antibody is un-conjugated
Application
All applications for ERBB3 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Specificity
The antibody detects endogenous level of Her3/ErbB3 only when phosphorylated at tyrosine 1328.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Immunogen
Peptide sequence around phosphorylation site of pTyr1328 (P-D-Y (p) -W-H) derived from Human Her3, ErbB3. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100 Immunofluorescence: 1:100-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for ERBB3
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Target
ERBB3
(Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
Alternative Name
Her3/ErbB3 (ERBB3 Products )
Synonyms
ErbB-3 antibody, HER3 antibody, LCCS2 antibody, MDA-BF-1 antibody, c-erbB-3 antibody, c-erbB3 antibody, erbB3-S antibody, p180-ErbB3 antibody, p45-sErbB3 antibody, p85-sErbB3 antibody, ERBB3 antibody, C76256 antibody, Erbb-3 antibody, Erbb3r antibody, Her3 antibody, nuc-ErbB3 antibody, erb-b2 receptor tyrosine kinase 3 antibody, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antibody, ERBB3 antibody, Erbb3 antibody
Background
Binds and is activated by neuregulins and NTAK.
Molecular Weight
185 kDa
NCBI Accession
NP_001005
UniProt
P21860
Pathways
RTK Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway
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