ERBB3 antibody (AA 1287-1291)

Catalog No. ABIN363077

The Rabbit Polyclonal anti-ERBB3 antibody is suitable to detect ERBB3 in samples from Human. It has been validated for IF.

Quick Overview for ERBB3 antibody (AA 1287-1291) (ABIN363077)

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERBB3 antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-ERBB3 Antibody

Binding Specificity: AA 1287-1291

Specificity: The antibody detects endogenous level of total Her3/ErbB3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen: Peptide sequence around AA 1287-1291 (Q-G-Y-E-E) derived from Human Her3, ErbB3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype: IgG

Application Details

Application Notes: Immunofluorescence: 1:100-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for ERBB3

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Alternative Name: Her3/ErbB3

Background: Binds and is activated by neuregulins and NTAK.

Molecular Weight: 185 kDa

NCBI Accession: NP_001005

UniProt: P21860

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway