ATM antibody (pSer1981)

Catalog No. ABIN363181

This Mouse Monoclonal antibody specifically detects ATM in WB, IHC, IF and ICC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ATM antibody (pSer1981) (ABIN363181)

Target: ATM (Ataxia Telangiectasia Mutated (ATM))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 10H11-E12

Product Details anti-ATM Antibody

Binding Specificity: pSer1981

Specificity: Reacts with human, mouse and rat pS1981 ATM kinase

Cross-Reactivity (Details): Does not react with protein from dog.

Purification: Purified (protein G)

Immunogen: Synthetic peptide from ATM with a phosphorylated serine 1981

Isotype: IgG1 kappa

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC(1:1000) IHC(1:2000) WB(1:1000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.97 mg/mL

Buffer: Tris-glycine, 150 mM NaCl, Sodium azide 0.05 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Target Details for ATM

Target: ATM (Ataxia Telangiectasia Mutated (ATM))

Alternative Name: Serine-Protein Kinase ATM

Background: Belongs to the PI3/PI4-kinase family. ATM subfamily.

UniProt: Q13315

Pathways: p53 Signaling, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus