AIP antibody

Catalog No. ABIN363261

The Mouse Monoclonal anti-AIP antibody (Clone 35-2) (ABIN363261) specifically detects AIP in WB, IHC, IP, ICC, IHC (p), IF and ChIP. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for AIP antibody (ABIN363261)

Target: AIP (Aryl Hydrocarbon Receptor Interacting Protein (AIP))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This AIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)

Clone: 35-2

Product Details anti-AIP Antibody

Specificity: Reacts with human ~38 kDa AIP

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Cross reacts with mouse and rat protein.

Purification: Cell culture supernatant

Immunogen: Bacterially expressed human AIP/ARA9.

Isotype: IgG1

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB1:1000 ChIP 1:10-1:500 IP1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: , Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Target Details for AIP

Target: AIP (Aryl Hydrocarbon Receptor Interacting Protein (AIP))

Alternative Name: AH Receptor-Interacting Protein (AIP)

Background: AIP/ARA9 plays a positive role in AHR-mediated signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. It was originally identified as a negative regulator of hepatitis B virus X-associated protein (hence named XAP2 also) and later was shown as Hsp90-associated protein which specifically interacts with AhR leading to regulation of AhR intracellular localization as well as protein stability via inhibition of AhR ubiquitination.

Gene ID: 9049

UniProt: O00170