XRCC3 antibody

Catalog No. ABIN363391

This Rabbit Polyclonal antibody specifically detects XRCC3 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for XRCC3 antibody (ABIN363391)

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XRCC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-XRCC3 Antibody

Specificity: Reacts with human 38 kDa XRCC3 protein

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Not reacts in mouse. No cross-reactivity with XRCC2, RAD51, RAD51B, RAD51C, or RAD51D. Not tested in other species.

Purification: Antigen affinity purified

Immunogen: Synthetic partial peptide of human XRCC3

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/5 000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, Sodium azide 0.05 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Target Details for XRCC3

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Alternative Name: DNA Repair Protein XRCC3

Background: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C. Involved in Breast cancer.

Gene ID: 7517

Pathways: DNA Damage Repair