ENPEP antibody (FITC)

Catalog No. ABIN371042

The Rat Monoclonal anti-ENPEP antibody is suitable to detect ENPEP in samples from Mouse. It has been validated for FACS.

Quick Overview for ENPEP antibody (FITC) (ABIN371042)

Target: ENPEP (Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ENPEP antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: FG35-4

Product Details anti-ENPEP Antibody (FITC)

Specificity: This antibody is specific to BP1 (Ly-51/6C3).

Characteristics: Synonyms: EAP, Aminopeptidase A, ENPEP, Differentiation antigen gp160

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.12)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for ENPEP

Target: ENPEP (Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP))

Alternative Name: CD249 / Glutamyl Aminopeptidase

Background: BP1, also known as Ly51/6C3 antigen, is a type II homodimeric transmembrane glycoprotein formed by two disulfide-linked chains of 140 kDa. (Ref.1,2) Originally identified on the surface of pre-B cell lymphomas (Ref.1,3) the cDNA encoding BP1 has been cloned and found to represent Aminopeptidase A. (Ref.4,5) It is expressed at high levels on bone marrow stromal cell lines which support in vitro B lymphopoiesis and on a wide variety of Mouse tissues known to possess aminopeptidase activity. (Ref.6-8) Subsets of normal bone marrow pre-B and B cells express low levels of BP1, which is rapidly upregulated on pre-B cells in the presence of IL-7. (Ref.9,10) The BP1 marker is commonly used to identify B cells in different stages of development. (Ref.11)Synonyms: Aminopeptidase A, Differentiation antigen gp160, EAP, ENPEP

Gene ID: 13809

UniProt: P16406

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones