IL-5 antibody

Catalog No. ABIN371620

Product Details anti-IL-5 Antibody

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-5 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), ELISA (Capture), ELISA (Detection)

Specificity: This antibody is specific to Human Interleukin-5/IL-5. (Ref.1-4)

Characteristics: Synonyms: IL-5, B-cell differentiation factor I, Eosinophil differentiation factor, T-cell replacing factor,TRF

Purification: Purified

Immunogen: COS-expressed recombinant human IL-5.

Clone: JES1-5A10

Isotype: IgG2a

Application Details

Application Notes: ELISA: Useful useful as a Detection/Capture antibody in a Sandwich ELISA for quantifyinghuman IL-5 protein levels. (Ref.1-5)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate buffered saline, pH 8.2 without preservatives or amine-containing buffer salts.

Preservative: Without preservative

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for IL-5

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Alternative Name: Interleukin-5 / IL5 (IL5 Products)

Synonyms: EDF antibody, IL-5 antibody, TRF antibody, Il-5 antibody, IL5 antibody, interleukin 5 antibody, IL5 antibody, Il5 antibody

Background: Human Interleukin 5 (IL5) is a cytokine produced primarily by activated T lymphocytes. It exists as an antiparallel disulfide-linked homodimeric glycoprotein with 115 amino-acid residues in each chain. Known also as EDG (eosinophil differentiating factor), functions predominantly as an eosinophilopoietic factor. Analysis of its crystal structure reveals a novel two-domain structure, with each domain showing significant homology to the cytokine fold in GM-CSF, M-CSF, IL2, IL4 and growth hormone. Human and Mouse IL5 have 70 % amino acid sequence homology.Synonyms: B-cell differentiation factor I, Eosinophil differentiation factor, IL-5, T-cell replacing factor, TRF

Gene ID: 3567

UniProt: P05113

Pathways: JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour