TRF1 antibody (C-Term)

Catalog No. ABIN374172

The Goat Polyclonal anti-TRF1 antibody (ABIN374172) specifically detects TRF1 in WB. The antibody is reactive with Human samples.

Quick Overview for TRF1 antibody (C-Term) (ABIN374172)

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This TRF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRF1 Antibody

Binding Specificity: C-Term

Sequence: C-TMKKLKLISS DSED

Specificity: This antibody detects TERF1 at C-Term.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the C Terminus of the protein sequence according to NP_003209.2, NP_059523.2. Genename: TERF1

Application Details

Application Notes: Peptide ELISA: Limit dilution 1: 8000. Western blot: 1-3 μg/mL. Approx 60-65 kDa and 45 kDa bands seen in HeLa lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Target Details for TRF1

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Alternative Name: TERF1

Background: Synonyms: NIMA-interacting protein 2, PIN2, TRBF1, TRF, TRF1, TTAGGG repeat-binding factor 1, Telomeric protein Pin2/TRF1, Telomeric repeat-binding factor 1

Gene ID: 7013

NCBI Accession: NP_003209

UniProt: P54274

Pathways: Cell Division Cycle, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity