Retinoblastoma Protein (Rb) antibody

Catalog No. ABIN378930

The Mouse Monoclonal anti-Retinoblastoma Protein (Rb) antibody has been validated for WB, IHC and IP. It is suitable to detect Retinoblastoma Protein (Rb) in samples from Human.

Quick Overview for Retinoblastoma Protein (Rb) antibody (ABIN378930)

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoblastoma Protein (Rb) antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: 1F8

Product Details anti-Retinoblastoma Protein (Rb) Antibody

Specificity: Recognizes human retinoblastoma gene protein. Rb gene, a prototype of tumor suppressor genes has been associated with development and/or progression of bladder cancer as well as sarcoma and small cell lung cancer. Functional Rb gene loss has been reported to occur in bladder cancer and osteosarcoma. A significantly poorer tumor-free survival rate was noted for those patients who had a tumor with an altered Rb protein with or without vascular invasion.

Purification: Ig fraction

Immunogen: Recombinant human Rb protein.

Type of Immunogen: Recombinant protein

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: IHC, IP (1:50), WB (1:50 - 1:100)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Buffer contains: 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for Retinoblastoma Protein (Rb)

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Alternative Name: RB1 / Retinoblastoma / RB

Background: Name/Gene ID: RB1

Synonyms: RB1, p105-Rb, Osteosarcoma, PRb, Retinoblastoma, Retinoblastoma 1, OSRC, RB, Pp110

Gene ID: 5925

Pathways: Mitotic G1-G1/S Phases