CD46 antibody

Catalog No. ABIN379988

The Mouse Monoclonal anti-CD46 antibody is suitable to detect CD46 in samples from Human. It has been validated for IHC, IHC (p) and IHC (fro).

Quick Overview for CD46 antibody (ABIN379988)

Target: CD46

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD46 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 13-42

Product Details anti-CD46 Antibody

Specificity: The antigen is CD46, the epitope is localized in the first two short consensus repeats. Antigen distribution: Isolated cells: The antigen is widely expressed on human cells except erythrocytes. It can also be found as a soluble protein in serum and saliva. Many human cell lines express CD46, e.g. U937, HeLa. Specificity: Human: CD46. Other species: positive in African green monkey, other species not tested.

Purification: Affinity purified

Immunogen: human U-251 cells

Isotype: IgG1

Application Details

Application Notes: Approved: IHC, IHC-Fr (1:50), IHC-P (1:200 - 1:400)

Usage: For IHC-P, Proteinase K pretreatment for antigen retrieval is recommended.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

Target Details for CD46

Target: CD46

Alternative Name: MCP / CD46

Background: Name/Gene ID: CD46

Synonyms: CD46, AHUS2, CD46 antigen, MCP, Measles virus receptor, TLX, MIC10, TRA2.10, Membrane cofactor protein

Gene ID: 4179

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization