KPNA4 antibody (C-Term)

Catalog No. ABIN388688

There is 1 publication for this product available. The Rabbit Polyclonal anti-KPNA4 antibody is suitable to detect KPNA4 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for KPNA4 antibody (C-Term) (ABIN388688)

Target: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KPNA4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB9325

Product Details anti-KPNA4 Antibody

Binding Specificity: AA 1-30, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Importin alpha-3 (KPNA4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the C-terminal region of human Importin alpha-3 (KPNA4).

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-KPNA4 antibody (ABIN388688)

Zhang, Dong, Zhang, He, Chen, Cao, Li, Xiao, Lu, Pan: "Identification of a novel nuclear localization signal of baculovirus late expression factor 11." in: Virus research, Vol. 184, pp. 111-9, (2014) (PubMed).

Target Details for KPNA4

Target: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Alternative Name: Importin alpha-4 (KPNA4)

Background: The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

Molecular Weight: 57887

Gene ID: 3840

NCBI Accession: NP_002259

UniProt: O00629

Pathways: Protein targeting to Nucleus