CDK7 antibody (pThr170)
-
- Target See all CDK7 Antibodies
- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
-
Binding Specificity
- pThr170
-
Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This CDK7 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)
- Predicted Reactivity
- M
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This CDK7 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T170 of human CDK7.
- Clone
- RB07518
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CDK7 Primary Antibody
-
-
- Application Notes
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. DB: 1:500
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
- Expiry Date
- 6 months
-
- Target
- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
- Alternative Name
- CDK7 (CDK7 Products)
- Background
- The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
- Molecular Weight
- 39038
- Gene ID
- 1022
- NCBI Accession
- NP_001790
- UniProt
- P50613
- Pathways
- Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
-