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Retinoblastoma 1 antibody (pSer612)

This anti-Retinoblastoma 1 antibody is a Rabbit Polyclonal antibody detecting Retinoblastoma 1 in WB and IHC (p). Suitable for Human. This Primary Antibody has been cited in 1 publication.
Catalog No. ABIN389643

Quick Overview for Retinoblastoma 1 antibody (pSer612) (ABIN389643)

Target

See all Retinoblastoma 1 (RB1) Antibodies
Retinoblastoma 1 (RB1)

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Retinoblastoma 1 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB7659
  • Binding Specificity

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    pSer612

    Specificity

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S612 of human RB

    Purification

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    Immunogen

    This RB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S612 of human RB.

    Isotype

    Ig Fraction
  • Application Notes

    WB = 1:1000, IHC (p) = 1:50-100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.38 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C/-20 °C

    Storage Comment

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Expiry Date

    6 months
  • Rizzolio, Lucchetti, Caligiuri, Marchesi, Caputo, Klein-Szanto, Bagella, Castronovo, Giordano: "Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1." in: Cell death and differentiation, Vol. 19, Issue 7, pp. 1152-61, (2012) (PubMed).

  • Target

    Retinoblastoma 1 (RB1)

    Alternative Name

    RB

    Background

    Synonyms: Retinoblastoma-associated protein, PP110, P105-RB, RB, RB1,

    Molecular Weight

    106159 DA

    Gene ID

    5925

    UniProt

    P06400

    Pathways

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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