ATF2 antibody (pSer322)

Catalog No. ABIN389760

The Rabbit Polyclonal anti-ATF2 antibody (Clone RB10901) (ABIN389760) specifically detects ATF2 in DB. The antibody is reactive with Human samples.

Quick Overview for ATF2 antibody (pSer322) (ABIN389760)

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF2 antibody is un-conjugated

Application: Dot Blot (DB)

Clone: RB10901

Product Details anti-ATF2 Antibody

Binding Specificity: pSer322

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATF2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S322 of human ATF2.

Isotype: Ig Fraction

Application Details

Application Notes: DB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ATF2

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Alternative Name: ATF2

Background: ATF2 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.

Molecular Weight: 54537

Gene ID: 1386

NCBI Accession: NP_001243019, NP_001243020, NP_001243021, NP_001243022, NP_001243023, NP_001871

UniProt: P15336

Pathways: MAPK Signaling, RTK Signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades