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TDG antibody (C-Term)

TDG Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB19894 unconjugated
Catalog No. ABIN390560
  • Target See all TDG Antibodies
    TDG (Thymine-DNA Glycosylase (TDG))
    Binding Specificity
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 281-310, C-Term
    Reactivity
    • 46
    • 20
    • 12
    • 2
    • 1
    Human
    Host
    • 37
    • 10
    Rabbit
    Clonality
    • 40
    • 8
    Polyclonal
    Conjugate
    • 41
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TDG antibody is un-conjugated
    Application
    • 37
    • 11
    • 11
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This TDG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the C-terminal region of human TDG.
    Clone
    RB19894
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TDG Primary Antibody
  • Application Notes
    WB: 1:1000. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    TDG (Thymine-DNA Glycosylase (TDG))
    Alternative Name
    TDG (TDG Products)
    Synonyms
    5-MCDG antibody, wu:fb44b11 antibody, zgc:110622 antibody, MGC82456 antibody, MGC89441 antibody, E130317C12Rik antibody, JZA-3 antibody, Jza1 antibody, hTDG antibody, thymine DNA glycosylase antibody, thymine DNA glycosylase, tandem duplicate 1 antibody, putative g/t mismatch-specific thymine DNA glycosylase antibody, G/T mismatch-specific thymine DNA glycosylase antibody, thymine DNA glycosylase S homeolog antibody, thymine-DNA glycosylase antibody, TDG antibody, tdg.1 antibody, Smp_149220 antibody, Tsp_05734 antibody, tdg.S antibody, tdg antibody, Tdg antibody
    Background
    The protein TDG belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine.
    Molecular Weight
    46053
    Gene ID
    6996
    NCBI Accession
    NP_003202
    UniProt
    Q13569
    Pathways
    DNA Damage Repair, Chromatin Binding
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