CKB antibody (C-Term)

Catalog No. ABIN391074

The Rabbit Polyclonal anti-CKB antibody (Clone RB05444) (ABIN391074) specifically detects CKB in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for CKB antibody (C-Term) (ABIN391074)

Target: CKB (Creatine Kinase, Brain (CKB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CKB antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB05444

Product Details anti-CKB Antibody

Binding Specificity: AA 240-270, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Creatine Kinase B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-270 amino acids from the C-terminal region of human Creatine Kinase B.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CKB

Target: CKB (Creatine Kinase, Brain (CKB))

Alternative Name: Creatine Kinase BB (CKB)

Background: Creatine Kinase (CK) is a dimeric enzyme composed of either M- or B-type subunits. The resulting isoenzymes are expressed at varying levels in different tissues. CK-BB, a cytoplasmic predominantly found in brain tissues, participates in energy homeostasis, reversibly catalyzing the transfer of a phosphate group between ATP and target proteins such as a creatine phosphate. CK-BB exists in normally neglible amounts in the serum of adults, overexpression of CK-BB is associated with cancers of the breast, ovary, prostate, colon, and in small-cell lung cancer. Global assessment of changes in serum levels of CK-BB, CK-MB and CK-MM, are used as a marker for myocardial infarction.

Molecular Weight: 42644

Gene ID: 1152

NCBI Accession: NP_001814

UniProt: P12277