TMPRSS2 antibody (AA 314-343)

Catalog No. ABIN391564

This Rabbit Polyclonal antibody specifically detects TMPRSS2 in WB and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for TMPRSS2 antibody (AA 314-343) (ABIN391564)

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB18785

Product Details anti-TMPRSS2 Antibody

Binding Specificity: AA 314-343

Predicted Reactivity: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This TMPRSS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the Central region of human TMPRSS2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TMPRSS2

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Alternative Name: TMPRSS2

Background: TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.

Molecular Weight: 53859

Gene ID: 7113

NCBI Accession: NP_001128571, NP_005647

UniProt: O15393

Pathways: SARS-CoV-2 Protein Interactome