RPS6KB2 antibody (AA 243-272)

Catalog No. ABIN392547

The Rabbit Polyclonal anti-RPS6KB2 antibody (Clone RB11689) (ABIN392547) specifically detects RPS6KB2 in WB. The antibody is reactive with Human and Rat samples.

Quick Overview for RPS6KB2 antibody (AA 243-272) (ABIN392547)

Target: RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS6KB2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB11689

Product Details anti-RPS6KB2 Antibody

Binding Specificity: AA 243-272

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This RPS6KB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-272 amino acids from the Central region of human RPS6KB2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for RPS6KB2

Target: RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))

Alternative Name: RPS6KB2

Background: RPS6KB2 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

Molecular Weight: 53455

Gene ID: 6199

NCBI Accession: NP_003943

UniProt: Q9UBS0

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway