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BAI1 antibody (C-Term)

BAI1 Reactivity: Human, Mouse WB, IHC (p), FACS Host: Rabbit Polyclonal RB02096 unconjugated
Catalog No. ABIN392804
  • Target See all BAI1 Antibodies
    BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
    Binding Specificity
    • 15
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1537-1567, C-Term
    Reactivity
    • 41
    • 13
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 40
    • 1
    Rabbit
    Clonality
    • 40
    • 1
    Polyclonal
    Conjugate
    • 21
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAI1 antibody is un-conjugated
    Application
    • 18
    • 15
    • 13
    • 13
    • 12
    • 12
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This BAI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1537-1567 amino acids from the C-terminal region of human BAI1.
    Clone
    RB02096
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
    Alternative Name
    BAI1 (BAI1 Products)
    Synonyms
    BAI1 antibody, GDAIF antibody, B830018M07Rik antibody, R75078 antibody, mKIAA4089 antibody, brain-specific angiogenesis inhibitor 1 antibody, adhesion G protein-coupled receptor B1 antibody, BAI1 antibody, ADGRB1 antibody, LOC100228084 antibody, Adgrb1 antibody
    Background
    Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas.
    Molecular Weight
    173501
    Gene ID
    575
    NCBI Accession
    NP_001693
    UniProt
    O14514
    Pathways
    p53 Signaling
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