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BAI1 antibody (Internal Region)

BAI1 Reactivity: Human, Mouse, Rat IHC, WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6257957
  • Target See all BAI1 Antibodies
    BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
    Binding Specificity
    • 15
    • 10
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 41
    • 13
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 40
    • 1
    Rabbit
    Clonality
    • 40
    • 1
    Polyclonal
    Conjugate
    • 21
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAI1 antibody is un-conjugated
    Application
    • 17
    • 14
    • 13
    • 13
    • 13
    • 12
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    BAI1 Antibody detects endogenous levels of total BAI1.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human BAI1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product BAI1 Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
    Alternative Name
    BAI1 (BAI1 Products)
    Synonyms
    BAI1 antibody, GDAIF antibody, B830018M07Rik antibody, R75078 antibody, mKIAA4089 antibody, brain-specific angiogenesis inhibitor 1 antibody, adhesion G protein-coupled receptor B1 antibody, BAI1 antibody, ADGRB1 antibody, LOC100228084 antibody, Adgrb1 antibody
    Background

    Description: Phosphatidylserine receptor which enhances the engulfment of apoptotic cells (PubMed:24509909). Also mediates the binding and engulfment of Gram-negative bacteria (PubMed:26838550). Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity (PubMed:26838550). In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells (PubMed:24509909). Promotes myoblast fusion (By similarity). Activates the Rho pathway in a G-protein-dependent manner (PubMed:23782696). Inhibits MDM2-mediated ubiquitination and degradation of DLG4/PSD95, promoting DLG4 stability and regulating synaptic plasticity (By similarity). Required for the formation of dendritic spines by ensuring the correct localization of PARD3 and TIAM1 (By similarity). Potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53/TP53 signal in suppression of glioblastoma (PubMed:11875720).

    Gene: BAI1

    Molecular Weight
    174 kDa
    Gene ID
    575
    UniProt
    O14514
    Pathways
    p53 Signaling
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