PTPRG
(Protein tyrosine Phosphatase, Receptor Type, G (PTPRG))
Reactivity
Human, Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
This PTPRG antibody is un-conjugated
Application
Western Blotting (WB)
Clone
RB0553
Binding Specificity
AA 751-782
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This PTP gamma antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-782 amino acids from the Central region of human PTP gamma.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target
PTPRG
(Protein tyrosine Phosphatase, Receptor Type, G (PTPRG))
Alternative Name
PTP gamma
Background
PTPgamma is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. The gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.