CD86 antibody (PE)
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- Target See all CD86 Antibodies
- CD86
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD86 antibody is conjugated to PE
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- Purpose
- Mouse monoclonal antibody raised against native CD86.
- Specificity
- This antibody reacts with CD86 (B7-2), a 70 KDa type I transmembrane glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
- Cross-Reactivity
- Human
- Immunogen
- Native purified CD86 from human ARH-77 cell.
- Clone
- BU63
- Isotype
- IgG1
- Top Product
- Discover our top product CD86 Primary Antibody
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- Application Notes
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Flow Cytometry (20 µL in human blood cells 100 µL in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In PBS (0.2 % BSA, 0.09 % sodium azide)
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
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Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
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Suppression of colon inflammation by CD80 blockade: evaluation in two murine models of inflammatory bowel disease." in: Inflammatory bowel diseases, Vol. 14, Issue 4, pp. 458-70, (2008) (PubMed).
: "Insertion of host-derived costimulatory molecules CD80 (B7.1) and CD86 (B7.2) into human immunodeficiency virus type 1 affects the virus life cycle." in: Journal of virology, Vol. 78, Issue 12, pp. 6222-32, (2004) (PubMed).
: "
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Suppression of colon inflammation by CD80 blockade: evaluation in two murine models of inflammatory bowel disease." in: Inflammatory bowel diseases, Vol. 14, Issue 4, pp. 458-70, (2008) (PubMed).
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- Target
- CD86
- Alternative Name
- CD86 (CD86 Products)
- Synonyms
- B7-2 antibody, B7.2 antibody, B70 antibody, CD28LG2 antibody, LAB72 antibody, B7 antibody, CLS1 antibody, Cd28l2 antibody, ETC-1 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, TS/A-2 antibody, CD86 molecule antibody, CD86 antigen antibody, integrin subunit alpha 2b antibody, CD86 antibody, Cd86 antibody, Itga2b antibody
- Gene ID
- 942
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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