Herpes Simplex Virus Type 2 (HSV2) antibody

Catalog No. ABIN4369800

Product Details

Target: Herpes Simplex Virus Type 2 (HSV2)

Reactivity: Herpes simplex virus type 2

Host: Sheep

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunofluorescence (IF), ELISA, Western Blotting (WB), Enzyme Immunoassay (EIA), ELISA (Capture), Immunoassay (IA)

Purpose: Sheep polyclonal antibody raised against Herpes Simplex Virus Type-2.

Specificity: ICPs + late structural (virion) antigens. Does not react with HEp-2 cells. HSV Type-1 titer is 1:512 by indirect immunofluorescence.

Cross-Reactivity: Virus

Immunogen: Native from human Herpes Simplex Virus type 2 Strain G.

Isotype: IgG

Application Details

Application Notes: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 10 mM PBS, pH 7.2 (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References

Liu, Li, Zhang, Zhang, Hu: "HSV-2 glycoprotein gD targets the CC domain of tetherin and promotes tetherin degradation via lysosomal pathway." in: Virology journal, Vol. 13, Issue 1, pp. 154, (2016) (PubMed).

Luo, Hu, He, Wang, Zhang, Huang, Du, Zheng, Liu, Hu: "Contribution of N-linked glycans on HSV-2 gB to cell-cell fusion and viral entry." in: Virology, Vol. 483, pp. 72-82, (2015) (PubMed).

Liu, Luo, He, Zhang, Wang, Li, Huang, Hu, Griffin, Shattock, Hu: "Tetherin restricts HSV-2 release and is counteracted by multiple viral glycoproteins." in: Virology, Vol. 475, pp. 96-109, (2014) (PubMed).

Target Details

Target: Herpes Simplex Virus Type 2 (HSV2)

Alternative Name: Herpes Simplex Virus 2 / HSV2

Target Type: Virus