ENPP2 antibody (Middle Region)

Catalog No. ABIN453640

Product Details anti-ENPP2 Antibody

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENPP2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to Autotaxin.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human ENPP2

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ENPP2

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Alternative Name: Autotaxin / ENPP2 (ENPP2 Products)

Synonyms: ATX antibody, ATX-X antibody, AUTOTAXIN antibody, LysoPLD antibody, NPP2 antibody, PD-IALPHA antibody, PDNP2 antibody, Npps2 antibody, PD-Ialpha antibody, Pdnp2 antibody, MGC132047 antibody, atx antibody, zgc:63550 antibody, autotaxin antibody, enpp2 antibody, enpp2a antibody, enpp2b antibody, ectonucleotide pyrophosphatase/phosphodiesterase 2 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog antibody, ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog antibody, ENPP2 antibody, Enpp2 antibody, enpp2 antibody, enpp2.L antibody, enpp2.S antibody

Background: ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The protein is secreted and further processed to make the biologically active form.Synonyms: ATX, E-NPP 2, ENPP2, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Extracellular lysophospholipase D, PDNP2

Gene ID: 5168

NCBI Accession: NP_001035181

UniProt: Q13822