SREBF chaperone antibody (Middle Region)

Catalog No. ABIN453817

This Rabbit Polyclonal antibody specifically detects SREBF chaperone in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for SREBF chaperone antibody (Middle Region) (ABIN453817)

Target: SREBF chaperone (SCAP)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF chaperone antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SREBF chaperone Antibody

Binding Specificity: Middle Region

Specificity: This antibody reacts to SCAP.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human SCAP

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SREBF chaperone

Target: SREBF chaperone (SCAP)

Alternative Name: SCAP

Background: SCAP is a protein with a sterol sensing domain(SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.Synonyms: KIAA0199, SREBP cleavage-activating protein, Sterol regulatory element-binding protein cleavage-activating protein

Gene ID: 22937

NCBI Accession: NP_036367

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interactome