TSH receptor antibody (AA 180-229)

Catalog No. ABIN6743075

Product Details anti-TSH receptor Antibody

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Binding Specificity: AA 180-229

Reactivity: Human, Mouse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSH receptor antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human TSHR

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Pig (100%) Rat, Sheep, Dog, Bovine, Rabbit, Chicken (92%) Horse, Guinea pig (91%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa180-229 of human TSHR (P16473, NP_000360). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Mouse, Elephant, Pig (100%), Gibbon, Monkey, Marmoset, Rat, Sheep, Panda, Dog, Cat, Bovine, Bat, Rabbit, Opossum, Chicken (92%), Galago, Horse, Guinea pig (91%), Zebra finch (84%), Turkey (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Alternative Name: TSH Receptor / TSHR (TSHR Products)

Synonyms: CHNG1 antibody, LGR3 antibody, hTSHR-I antibody, AI481368 antibody, hypothroid antibody, hyt antibody, pet antibody, TSHRA antibody, TSH-R antibody, thyroid stimulating hormone receptor antibody, tshr antibody, TSHR antibody, Tshr antibody

Background: Name/Gene ID: TSHR
Subfamily: Glycoprotein hormone
Family: GPCR

Synonyms: TSHR, CHNG1, HTSHR-I, LGR3, Thyrotrophin receptor, TSH-R, TSH receptor, Thyrotropin receptor

Gene ID: 7253

NCBI Accession: NP_000360

UniProt: P16473

Pathways: Thyroid Hormone Synthesis