Insulin C-Peptide antibody
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- Target See all Insulin C-Peptide products
- Insulin C-Peptide
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Reactivity
- Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Insulin C-Peptide antibody is un-conjugated
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Application
- ELISA
- Specificity
- Recognizes rat C-peptide I. C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. In rats, two isoforms of proinsulin exists, the difference is two amino acid residues in the C-peptide, termed C-peptide I and C-peptide II. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+ concentration and subsequent stimulation of N+, K+-ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Recognizes rat C-peptide I and rat proinsulin. It does not recognize mouse C-peptide I Reacts very weakly with rat and mouse C-peptide II. May be used to detect rat C-peptide I in ELISA assays.
- Purification
- Affinity purified
- Immunogen
- Fragments of rat C-peptide conjugated to a carrier protein.
- Clone
- 6H1
- Isotype
- IgG1
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- Application Notes
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Approved: ELISA, SwELISA
Usage: ELISA: This product may be used in an indirect ELISA or as a detection antibody in a sandwich ELISA to detect rat C-peptide I together with LS-C58409 as capture reagent. - Comment
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Target Species of Antibody: Rat
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
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Short term: -20°C
Long term: -20°C.
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- Target
- Insulin C-Peptide
- Abstract
- Insulin C-Peptide Products
- Synonyms
- IDDM2 antibody, ILPR antibody, IRDN antibody, MODY10 antibody, insulin antibody, INS antibody
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