GAS6 antibody (AA 291-340)

Catalog No. ABIN484505

The Rabbit Polyclonal anti-GAS6 antibody is suitable to detect GAS6 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for GAS6 antibody (AA 291-340) (ABIN484505)

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAS6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-GAS6 Antibody

Binding Specificity: AA 291-340

Purpose: Gas6 Antibody

Specificity: Gas6 Polyclonal Antibody detects endogenous levels of Gas6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GAS6. AA range:291-340

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GAS6

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Alternative Name: GAS6

Background:

Synonyms: GAS6, AXLLG, Growth arrest-specific protein 6, GAS-6, AXL receptor tyrosine kinase ligand

Background: This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia. [provided by RefSeq, Aug 2014],

Gene Name: GAS6

Protein Name: Growth arrest-specific protein 6

Molecular Weight: 79 kDa

Gene ID: 2621

OMIM: 600441

UniProt: Q14393

Pathways: RTK Signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response