FZD2 antibody (AA 201-250)

Catalog No. ABIN486228

The Rabbit Polyclonal anti-FZD2 antibody (ABIN486228) specifically detects FZD2 in WB, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for FZD2 antibody (AA 201-250) (ABIN486228)

Target: FZD2 (Frizzled Family Receptor 2 (FZD2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-FZD2 Antibody

Binding Specificity: AA 201-250

Purpose: Frizzled-2 Antibody

Specificity: Frizzled-2 Polyclonal Antibody detects endogenous levels of Frizzled-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FZD2. AA range:201-250

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FZD2

Target: FZD2 (Frizzled Family Receptor 2 (FZD2))

Alternative Name: FZD2

Background:

Synonyms: FZD2, Frizzled-2, Fz-2, hFz2, FzE2

Background: frizzled class receptor 2(FZD2) Homo sapiens This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins.This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. [provided by RefSeq, Dec 2010],

Gene Name: FZD2

Protein Name: Frizzled-2

Molecular Weight: 63 kDa

Gene ID: 2535

OMIM: 600667

UniProt: Q14332

Pathways: WNT Signaling