EVI2B antibody (PE)

Catalog No. ABIN487441

Product Details anti-EVI2B Antibody (PE)

Target: EVI2B (Ecotropic Viral Integration Site 2B (EVI2B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EVI2B antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: This antibody recognizes CD361 / EVI2B, almost uncharacterized type I transmembrane protein with broad leukocyte expression, mostly in myeloid and B cells.

Purification: Size-exclusion chromatography

Clone: MEM-216

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole bloodor 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for EVI2B

Target: EVI2B (Ecotropic Viral Integration Site 2B (EVI2B))

Alternative Name: CD361 / EVI2B (EVI2B Products)

Synonyms: CD361 antibody, D17S376 antibody, EVDB antibody, Evi-2 antibody, Evi2 antibody, EVI2B antibody, ecotropic viral integration site 2B antibody, ecotropic viral integration site 2b antibody, EVI2B antibody, Evi2b antibody

Background: CD361, also known as EVI2B (Ecotropic Viral Integration site 2B) or EVDB, is a poorly characterized type I transmembrane protein, expressed from one of three genes embedded in intron 27b of the neurofibromatosis type 1 (NF1) gene. The DNA strand that is transcribed to produce CD361 is the complementary one to the strand encoding NF1. Murine homolog to human CD361 is associated with ecotropic viral insertions, which have been implicated in the expression of murine myeloid leukemias. CD361 has been also reported to be involved in melanocyte and keratinocyte differentiation. However, it is expressed mainly in peripheral blood and bone marrow.Synonyms: EVDB, Ecotropic viral integration site 2B protein homolog

Gene ID: 2124

UniProt: P34910