Lamin A/C antibody (HRP)

Catalog No. ABIN4880111

The HRP-conjugated Mouse Monoclonal anti-Lamin A/C antibody (Clone JOL2) (ABIN4880111) specifically detects Lamin A/C in WB, IHC and IP. The antibody is reactive with Human and Green Monkey samples.

Quick Overview for Lamin A/C antibody (HRP) (ABIN4880111)

Target: Lamin A/C (LMNA)

Reactivity: Human, Green Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lamin A/C antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: JOL2

Product Details anti-Lamin A/C Antibody (HRP)

Purpose: Lamin A+C Monoclonal Antibody [JOL2] - Horseradish Peroxidase (HRP)

Specificity: The antibody reacts with both recombinant and native lamin A and C. It has been shown to bind to an epitope between amino acids 464-572

Purification: Protein G

Immunogen: Recombinant human lamin A

Isotype: IgG1

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as a guideline try,IHC (P) at 4 μg/mL

Comment:

Myeloma/fusion partners:Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2-0/Ag4 myeloma cell line

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified IgG conjugated to Horseradish Peroxidase using InnovaBiosciences Lightning-Link®, supplied in Phosphate buffered saline(PBS) containing 0.01 % Thiomersal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Lamin A/C

Target: Lamin A/C (LMNA)

Alternative Name: Lamin A+C

Background: 70 kDa Lamin antibody,Cardiomyopathy dilated 1A (autosomal dominant) antibody,CDCD1 antibody,CDDCantibody,Charcot Marie Tooth Disease Axonal Type 2B1 antibody,CMD1A antibody,CMT2B1 antibody,EMD2antibody,FPL antibody,FPLD antibody,HGPS antibody,IDC antibody,Lamin A/C antibody,Lamin A/C Isoform 1Precursor antibody,Lamin A/C Isoform 2 antibody,Lamin A/C Isoform 3 antibody,LDP1 antibody,LFPantibody,LGMD1B antibody,Limb girdle muscular dystrophy 1B (autosomal dominant) antibody,LMN 1 antibody,LMN Aantibody,LMN C antibody,LMN1 antibody,LMNA antibody,LMNC antibody,NY REN 32 antigen antibody,PRO1antibody,Progeria 1 (Hutchinson Gilford Type) antibody,Renal carcinoma antigen NY REN 32 antibody,Renalcarcinoma antigen NYREN32 antibody

Gene ID: 103223838, 4000, 24672

OMIM: 150330

UniProt: P63331

Pathways: Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus