Integrin Alpha2b antibody

Catalog No. ABIN4880137

The Mouse Monoclonal anti-Integrin Alpha2b antibody has been validated for FACS, IP, IF, IHC (fro) and ICC. It is suitable to detect Integrin Alpha2b in samples from Human.

Quick Overview for Integrin Alpha2b antibody (ABIN4880137)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Clone: M148

Product Details anti-Integrin Alpha2b Antibody

Specificity: This antibody recognises integrin alpha 2b, a 110-130 kDa transmembrane protein that is also known as CD41. CD41 associates with the integrin CD61 to form the CD41/CD61 (GPIIb/IIIa) heterodimer, a fibronectin receptor expressed in platelets. The antibody M148 binds to some medulloblastoma and neuroblastoma cells and rhabdomyosarcoma and certain other solid tumours. No binding is observed to marrow constituents other than platelets and megakaryocytes. The antibody M148 prevents aggregation of platelets.

Purification: Purified on protein A from tissue culture supernatant.

Immunogen: Homogenized human medulloblastoma tissue.

Isotype: IgG1

Application Details

Application Notes: Optimal antibody dilution should be determined by titration

Comment:

Myeloma, fusion partners: Cells from immunized Balb/c mice were fused with the P3X63Ag8.653 myeloma cell line

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified IgG supplied in Phosphate buffered saline (PBS) containing 0.09 % Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: CD41

Gene ID: 3689

OMIM: 607759

UniProt: P20701

Pathways: Integrin Complex